Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905801 | 0.87 | ABCB1 (0.52) | LMNASMN1; SMN2HTTKAT2BMEN1 | |
| SCHEMBL4065908 | 0.82 | PREP (0.56) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL21528072 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2HTTKEAP1NFE2L2 | |
| SCHEMBL21528073 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2HTTKEAP1NFE2L2 | |
| SCHEMBL31091787 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2HTTKEAP1NFE2L2 | |
| SCHEMBL21528098 | 0.78 | LMNA (0.59) | LMNASMN1; SMN2HTTKAT2BMEN1 | |
| SCHEMBL27225229 | 0.76 | ALDH1A1 (0.51) | GAADPP7TGM2DPP4ALDH1A1 | |
| SCHEMBL26093625 | 0.75 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2HTTKAT2BMEN1 | |
| SCHEMBL26093627 | 0.75 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2HTTKAT2BMEN1 | |
| SCHEMBL5041382 | 0.75 | SIGMAR1 (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |
| EP-1605938-A4 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| EP-1605938-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004087145-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |