Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905807 | 0.86 | PREP (0.50) | PREPALDH1A1KDM1ARCOR1GAA | |
| SCHEMBL4069289 | 0.82 | LMNA (0.49) | PREPALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL8007264 | 0.82 | PREP (0.53) | PREPALDH1A1KDM1ALMNASMN1; SMN2 | |
| SCHEMBL8008130 | 0.79 | SYK (0.45) | PREPCTSL | |
| SCHEMBL27225229 | 0.79 | ALDH1A1 (0.51) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL22811402 | 0.79 | PREP (0.54) | PREPALDH1A1KDM1ALMNASMN1; SMN2 | |
| SCHEMBL2084721 | 0.79 | PREP (0.54) | PREPALDH1A1KDM1ALMNASMN1; SMN2 | |
| SCHEMBL11386013 | 0.78 | PREP (0.76) | PREPALDH1A1LMNASMN1; SMN2CTSL | |
| SCHEMBL4051763 | 0.78 | PREP (0.43) | PREPCTSLCTSKCYP3A4CTSS | |
| SCHEMBL17293278 | 0.78 | PREP (0.51) | PREPALDH1A1KDM1ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |