Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FGB | P02675 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4061577 | 0.80 | P2RX3 (0.48) | POLBGAAGFERP2RX3P2RX2 | |
| SCHEMBL27316536 | 0.78 | P2RX3 (0.53) | POLBGAAGFERP2RX3P2RX2 | |
| SCHEMBL4239206 | 0.78 | IRAK4 (0.44) | POLBALDH1A1P2RX3P2RX2MEN1 | |
| SCHEMBL397150 | 0.77 | ALDH1A1 (0.44) | POLBGAAALDH1A1TDP1ADRA2B | |
| SCHEMBL4246550 | 0.77 | BRD4 (0.52) | ALDH1A1L3MBTL1P2RX3P2RX2MEN1 | |
| SCHEMBL4060627 | 0.75 | P2RX3 (0.45) | POLBGAAGFERALDH1A1ADRA2B | |
| SCHEMBL14616007 | 0.73 | PDCD1 (0.46) | POLBGAAALDH1A1TDP1ADRA2B | |
| SCHEMBL13848266 | 0.73 | L3MBTL1 (0.54) | ALDH1A1PTGS1L3MBTL1MEN1KMT2A | |
| SCHEMBL13848278 | 0.73 | PARP14 (0.51) | ALDH1A1L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL17454722 | 0.73 | ALDH1A1 (0.59) | ALDH1A1PTGS1L3MBTL1ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |
| WO-2009066060-A2 | 4-SUBSTITUTED-6-ISOPROPYL-BENZENE-1,3-DIOL COMPOUNDS AND THEIR USE | TOPOTARGET A/S (DK) | 2009-05-28 | — | — | WO | disclosed |