Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15393644 | 0.81 | NPC1 (0.53) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7129800 | 0.78 | MAPT (0.80) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8535923 | 0.78 | SRD5A2 (0.69) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1114930 | 0.77 | RAB9A (0.56) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL10994744 | 0.77 | SRD5A2 (0.68) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL30935799 | 0.76 | MAPT (0.63) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL1115098 | 0.76 | MAPT (0.63) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL7786912 | 0.75 | SRD5A2 (0.66) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL10967373 | 0.75 | SRD5A2 (0.66) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL10968921 | 0.75 | SRD5A2 (0.66) | SRD5A2RAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058396-A1 | NEGATIVE BIREFRINGENT OPTICAL FILMS WITH FLAT OR REVERSED BIREFRINGENCE WAVELENGTH DISPERSIONS FOR LIQUID CRYSTAL DISPLAYS | AKRON POLYMER SYSTEMS INC. (US) | 2009-05-07 | — | — | WO | disclosed |