Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GABRP | O00591 | 4/20 | 0.36 |
| ▸ | GABRD | O14764 | 4/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.36 |
| ▸ | GABRE | P78334 | 4/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955334 | 0.80 | KDM4E (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL6268309 | 0.79 | GABRA1 (0.35) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3943265 | 0.78 | CYP2A6 (0.49) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL4072714 | 0.76 | GSK3B (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4067752 | 0.76 | HSD17B10 (0.39) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL19179966 | 0.76 | GPR35 (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL9234958 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL6260071 | 0.73 | KDM4E (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18886844 | 0.73 | GAA (0.48) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL5260106 | 0.73 | KDM4E (0.48) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036906-A1 | Azaindoles as inhibitors of soluble adenylate cyclase | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |