Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.63 |
| ▸ | DEGS1 | O15121 | 7/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212859 | 0.88 | HCAR3 (0.53) | HCAR3DEGS1KDM4ERAB9ATP53 | |
| SCHEMBL217496 | 0.85 | NNMT (0.49) | HCAR3KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL26227296 | 0.79 | HDAC1 (0.51) | HCAR3DEGS1MAPT | |
| SCHEMBL30552385 | 0.79 | HDAC1 (0.51) | HCAR3DEGS1MAPT | |
| SCHEMBL22242773 | 0.79 | PTGS1 (0.77) | HCAR3DEGS1PTGS1KDM4ERAB9A | |
| SCHEMBL11308749 | 0.78 | HCAR3 (0.77) | HCAR3DEGS1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL2664544 | 0.77 | HCAR3 (1.00) | HCAR3DEGS1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL22444727 | 0.77 | P4HTM (0.57) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL28102450 | 0.76 | HCAR3 (0.72) | HCAR3DEGS1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8483127 | 0.76 | HDAC1 (0.72) | KDM4ESMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |