Sugi Predict

Sugi Predict / Compounds / SCHEMBL407154

SCHEMBL407154

SCHEMBL407154

CC(=O)c1ccc(C)c(Br)c1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 0.67
▸ SMN1; SMN2 Q16637 3/20 0.67
▸ NPC1 O15118 2/20 0.67
▸ HPGD P15428 5/20 0.58
▸ TSHR P16473 1/20 0.54
▸ MTOR P42345 6/20 0.51
▸ ALDH1A1 P00352 3/20 0.50
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ CYP2A6 P11509 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ LMNA P02545 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20919457 0.86 NPC1 (0.53) RAB9ASMN1; SMN2NPC1HPGDTSHR
SCHEMBL30950821 0.86 NPC1 (0.53) RAB9ASMN1; SMN2NPC1HPGDTSHR
SCHEMBL29784872 0.83 CHRNA1 (0.51) RAB9ASMN1; SMN2NPC1HPGDALDH1A1
SCHEMBL588574 0.83 CHRNA1 (0.51) RAB9ASMN1; SMN2NPC1HPGDALDH1A1
SCHEMBL29935432 0.83 HPGD (0.58) RAB9ASMN1; SMN2NPC1HPGDTSHR
SCHEMBL154862 0.83 HPGD (0.58) RAB9ASMN1; SMN2NPC1HPGDTSHR
SCHEMBL16954985 0.82 HPGD (0.52) RAB9ASMN1; SMN2NPC1HPGDTSHR
SCHEMBL3022646 0.82 MAPT (0.47) RAB9ASMN1; SMN2NPC1HPGDALDH1A1
Hydrochloric Acid SCHEMBL4912437 0.81 HPGD (0.56) RAB9ASMN1; SMN2NPC1HPGDTSHR
SCHEMBL1708334 0.81 HPGD (0.56) RAB9ASMN1; SMN2NPC1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4695242-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 — — EP disclosed
US-12516065-B2 Tertiary alcohols as PI3K-γ inhibitors INCYTE CORPORATION (US) 2026-01-06 — — US disclosed
US-12435060-B2 Acylamino bridged heterocyclic compound, and composition and application thereof BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2025-10-07 — — US disclosed
US-20250243206-A1 CRYSTALLINE FORMS OF A PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITOR INCYTE CORPORATION 2025-07-31 — — US disclosed
CN-120040450-A Crystalline forms of a phosphoinositide 3 kinase (PI 3K) inhibitor 因赛特公司 2025-05-27 — — CN disclosed
US-20250122173-A1 MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE REDX PHARMA LTD (GB) 2025-04-17 — — US disclosed
CN-113677683-B Crystalline forms of a phosphoinositide 3 kinase (PI 3K) inhibitor 因赛特公司 2025-01-14 — — CN disclosed
US-12173006-B2 Crystalline forms of a phosphoinositide 3-kinase (PI3K) inhibitor INCYTE CORPORATION (US) 2024-12-24 — — US disclosed
US-20240409807-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-12-12 — — US disclosed
EP-4466071-A1 MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE (ROCK) Redx Pharma Limited (GB) 2024-11-27 — — EP disclosed
WO-2006056854-A1 DIBENZYL AMINE COMPOUNDS AND DERIVATIVES PFIZER PRODUCTS INC. (US) 2006-06-01 — — WO disclosed
US-20060004216-A1 Polystyrene-supported palladacycle catalysts ACADEMIA SINICA (TW) 2006-01-05 — — US disclosed
WO-2004100960-A2 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-11-25 — — WO disclosed
US-5185363-A Administering for treatment of inflammatory diseases ABBOTT LABORATORIES (US) 1993-02-09 — — US disclosed
US-4209447-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1980-06-24 — — US disclosed
US-4160838-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1979-07-10 — — US disclosed
US-4139540-A FUNGICIDE, BACTERICIDE INTERMEDIATE JANSSEN PHARMACEUTICA N.V. (BE) 1979-02-13 — — US disclosed
US-4119641-A ANTIFUNGAL, ANTIBACTERIAL AGENTS JANSSEN PHARMACEUTICA N.V. (BE) 1978-10-10 — — US disclosed
US-4101664-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1978-07-18 — — US disclosed
US-4079062-A ANTIMICROBIAL, PLANT GROWTH REGULATORS; 1-(B-ARYL)ETHYL-1H-1,2,4-TRIAZOLE KETALS JANSSEN PHARMACEUTICA N.V. (BE) 1978-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004216-A1 Polystyrene-supported palladacycle catalysts NPY1R, NPY2R, CCNE1 RAB9A 1336/4885SMN1; SMN2 3300/4885NPC1 2929/4885
US-20250122173-A1 MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE ROCK1, ROCK2, RHOA RAB9A 384/4885SMN1; SMN2 2893/4885NPC1 1601/4885
US-12173006-B2 Crystalline forms of a phosphoinositide 3-kinase (PI3K) inhibitor PIK3CA, PIK3CD, PIK3CG RAB9A 1311/4885SMN1; SMN2 4341/4885NPC1 2793/4885
US-12435060-B2 Acylamino bridged heterocyclic compound, and composition and application thereof RIPK1, RIPK3, RIPK4 RAB9A 1133/4885SMN1; SMN2 1070/4885NPC1 2376/4885
US-20250243206-A1 CRYSTALLINE FORMS OF A PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITOR PIK3CA, PIK3CD, PIK3CG RAB9A 1311/4885SMN1; SMN2 4341/4885NPC1 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.