Sugi Predict

Sugi Predict / Compounds / SCHEMBL588574

SCHEMBL588574

SCHEMBL588574

CC(=O)c1ccc(Br)c(C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRNA1 P02708 1/20 0.51
▸ CHRNG P07510 1/20 0.51
▸ CHRNB1 P11230 1/20 0.51
▸ CHRNB2 P17787 1/20 0.51
▸ SLC6A2 P23975 1/20 0.51
▸ CHRNB4 P30926 1/20 0.51
▸ SLC6A4 P31645 1/20 0.51
▸ CHRNA3 P32297 1/20 0.51
▸ CHRNA4 P43681 1/20 0.51
▸ SLC6A3 Q01959 1/20 0.51
▸ CHRND Q07001 1/20 0.51
▸ RAB9A P51151 6/20 0.49
▸ NPC1 O15118 5/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ CYP2A6 P11509 1/20 0.47
▸ PKM P14618 3/20 0.46
▸ MAPT P10636 4/20 0.45
▸ ALDH1A1 P00352 3/20 0.45
▸ S100A4 P26447 1/20 0.44
▸ HTR1D P28221 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29784872 1.00 CHRNA1 (0.51) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
Bromide SCHEMBL28202862 0.96 CHRNA1 (0.49) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
Nitrous Acid SCHEMBL28202203 0.92 CHRNA1 (0.46) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL27581493 0.84 HTT (0.53) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL407154 0.83 RAB9A (0.67) RAB9ANPC1SMN1; SMN2CYP2A6MAPT
SCHEMBL141936 0.83 TSHR (0.52) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL3022646 0.82 MAPT (0.47) RAB9ANPC1SMN1; SMN2CYP2A6PKM
SCHEMBL16954457 0.82 CHRNA1 (0.46) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL482111 0.81 CHRNA1 (0.50) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
Hydrochloric Acid SCHEMBL27136895 0.81 TSHR (0.50) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324623-A Synthesis method of 2-methyl-4-acetyl benzoic acid 丽珠集团福州福兴医药有限公司 2024-07-12 — — CN claimed
CN-117510428-A Preparation process method of isoxazoline substituted benzamide compound 中国农业大学 2024-02-06 — — CN claimed
CN-107629029-A The preparation method of Wei Patawei intermediates 安徽省诚联医药科技有限公司 2018-01-26 — — CN claimed
EP-4081215-B1 METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE OHIO STATE INNOVATION FOUNDATION (US) 2026-05-20 — — EP disclosed
US-20250388541-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-25 — — US disclosed
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND SHOUYAO HOLDINGS BEIJING CO LTD (CN) 2025-07-10 — — US disclosed
US-12234218-B2 Heterocyclic compounds as modulators of mGluR7 PRAGMA THERAPEUTICS (FR) 2025-02-25 — — US disclosed
EP-4501912-A1 NOVEL HETEROCYCLIC COMPOUND Shouyao Holdings (Beijing) Co., Ltd. (CN) 2025-02-05 — — EP disclosed
CN-118324623-A Synthesis method of 2-methyl-4-acetyl benzoic acid 丽珠集团福州福兴医药有限公司 2024-07-12 — — CN disclosed
CN-118324623-A Synthesis method of 2-methyl-4-acetyl benzoic acid 丽珠集团福州福兴医药有限公司 2024-07-12 — — CN disclosed
CN-117776924-A Key intermediate of 4-acetyl-2-methylbenzoic acid and synthetic method thereof 苏州楚凯药业有限公司 2024-03-29 — — CN disclosed
EP-0533266-A1 Benzanilide derivatives as 5-HT1D antagonists GLAXO GROUP LIMITED (GB) 1993-03-24 — — EP disclosed
EP-0533268-A1 Benzanilide derivatives as 5-HT1D antagonists GLAXO GROUP LIMITED (GB) 1993-03-24 — — EP disclosed
EP-0191496-B1 TRIAZINE DERIVATIVES, A PROCESS FOR PREPARING THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-31 — — EP disclosed
CN-1004204-B Herbicide containing triazine derivative as active ingredient 出光兴产株式会社 1989-05-17 — — CN disclosed
US-4680054-A Triazine derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-07-14 — — US disclosed
EP-0191496-A2 Triazine Derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component IDEMITSU KOSAN COMPANY LIMITED (JP) 1986-08-20 — — EP disclosed
CN-86100884-A Process for preparing triazine derivatives and herbicides containing the derivatives as active ingredient — 1986-08-13 — — CN disclosed
US-4517318-A BENZOPHENONE AND TRANSITION METALCOMPOUNT ACCELERATOR Sekisu Kagaku Kogyo Kabushiki Kaisha (JP) 1985-05-14 — — US disclosed
US-4495315-A BENZOPHENONE-TYPE COMPOUNDS AS DEGRADING AGENT- TRANSITION METAL ACCELERATORS SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-01-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388541-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN SCN1B, CLIC1, HCN1 CHRNA1 131/4885CHRNG 376/4885CHRNB1 187/4885
US-12234218-B2 Heterocyclic compounds as modulators of mGluR7 GRM7, GRM1, GRM2 CHRNA1 199/4885CHRNG 153/4885CHRNB1 399/4885
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND MAPT, MNAT1, MAT2A CHRNA1 1825/4885CHRNG 4240/4885CHRNB1 2102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.