Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 9/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 9/20 | 0.33 |
| ▸ | KDR | P35968 | 8/20 | 0.33 |
| ▸ | SORD | Q00796 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071647 | 0.78 | ALDH1A1 (0.38) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL2127136 | 0.76 | FGFR1 (0.37) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL2129624 | 0.71 | CXCR4 (0.42) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL2125726 | 0.70 | MEN1 (0.37) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL4215152 | 0.69 | SORD (0.42) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL4070185 | 0.68 | ALDH1A1 (0.38) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL4070319 | 0.68 | FPR2 (0.37) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL4075983 | 0.68 | AGTR1 (0.39) | — | |
| SCHEMBL2126522 | 0.65 | KCNA5 (0.37) | FGFR1FGFR2FGFR4FGFR3KDR | |
| SCHEMBL2124334 | 0.65 | MEN1 (0.40) | FGFR1FGFR2FGFR4FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2055705-A1 | COMPOUND HAVING CYCLIC GROUP BOUND THERETO THROUGH SPIRO BINDING AND USE THEREOF | Ono Pharmaceutical CO., LTD. (JP) | 2009-05-06 | — | — | EP | disclosed |