SCHEMBL29241981

SCHEMBL29241981

O=CC1c2ccccc2-c2c1ccc1ccccc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.42
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPK1 P28482 2/20 0.40
LMNA P02545 1/20 0.40
WDR5 P61964 1/20 0.40
MAPT P10636 4/20 0.39
HPGD P15428 2/20 0.39
TDP2 O95551 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP3 P42574 1/20 0.39
HTT P42858 1/20 0.39
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28678943 0.82 CYP1B1 (0.39) DNMT1ALDH1A1KDM4EMAPK1LMNA
SCHEMBL28860047 0.76 LMNA (0.41) ALDH1A1LMNAHPGDHTTBLM
SCHEMBL11483094 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EMAPK1LMNAWDR5
SCHEMBL224931 0.75 GPR3 (0.41) ALDH1A1LMNABLMMEN1KMT2A
SCHEMBL29711937 0.75 GPR3 (0.41) ALDH1A1LMNABLMMEN1KMT2A
SCHEMBL28450164 0.74 HKDC1 (0.32) MAPK1HKDC1
SCHEMBL4072322 0.74 DNMT1 (0.42) DNMT1ALDH1A1KDM4EMAPK1LMNA
SCHEMBL9956780 0.73 ALDH1A1 (0.49) ALDH1A1KDM4EMAPK1LMNAMAPT
Hydrochloric Acid SCHEMBL8605086 0.72 DNMT1 (0.41) DNMT1ALDH1A1KDM4EMAPK1LMNA
Hydrochloric Acid SCHEMBL8606301 0.72 DNMT1 (0.41) DNMT1ALDH1A1KDM4EMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027362-A Benzofluorenone polymer and preparation method and application thereof 五邑大学 2024-05-14 CN disclosed
CN-118027362-A Benzofluorenone polymer and preparation method and application thereof 五邑大学 2024-05-14 CN disclosed