SCHEMBL4072354

SCHEMBL4072354

NC1(c2ccccc2)C=CC(=C2C=CC(N)(c3ccccc3)C=C2)C=C1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.38
MAOB P27338 11/20 0.35
MAOA P21397 10/20 0.35
KDM1A O60341 6/20 0.34
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680931 0.84 PNMT (0.44) PNMTMAOBMAOAKDM1ATAAR1
SCHEMBL28740433 0.84 PNMT (0.44) PNMTMAOBMAOAKDM1ATAAR1
SCHEMBL28752679 0.83 PNMT (0.31) PNMT
SCHEMBL18239154 0.73 PNMT (0.33) PNMTMAOBMAOAKDM1A
Hydrogen Sulfide SCHEMBL11119004 0.68 POLB (0.37)
SCHEMBL27480188 0.66 ALDH1A1 (0.41) PNMT
SCHEMBL23222658 0.65 ALDH1A1 (0.33)
SCHEMBL27676926 0.65 ALDH1A1 (0.42)
SCHEMBL4094369 0.62
SCHEMBL23857896 0.60 PNMT (0.43) PNMTMAOBMAOAKDM1ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107623088-B Light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-01-10 CN disclosed
CN-107623088-A Light-emitting component, light-emitting device, electronic equipment and lighting device 株式会社半导体能源研究所 2018-01-23 CN disclosed
CN-103840084-A Light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2014-06-04 CN disclosed
EP-2006278-A9 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2009-08-05 EP disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
EP-2006278-A2 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2008-12-24 EP disclosed
US-20080061678-A1 LIGHT EMITTING DEVICE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF SLC7A1, SLC43A1, SLC7A5 PNMT 3172/4885MAOB 4007/4885MAOA 4169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.