Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710374 | 0.92 | CHRNB2 (0.47) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL3449345 | 0.77 | CHRNB2 (0.32) | CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL10463079 | 0.76 | CA2 (0.41) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL3448403 | 0.75 | SLC6A1 (0.37) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL4840663 | 0.75 | HPGD (0.45) | HPGD | |
| SCHEMBL3448296 | 0.74 | SLC6A1 (0.36) | CA2CHKACHRNB2CHRNA3CHRNA4 | |
| SCHEMBL8024244 | 0.74 | HPGD (0.48) | HPGD | |
| SCHEMBL6656408 | 0.74 | HPGD (0.48) | HPGD | |
| SCHEMBL6695180 | 0.74 | HPGD (0.48) | HPGD | |
| SCHEMBL4261203 | 0.74 | HPGD (0.48) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065053-A1 | CELL DEATH INHIBITOR | Takeda Pharmaceutical Company Limited (JP) | 2009-06-03 | — | — | EP | disclosed |
| EP-1897880-A1 | 1,3-BENZOTHIAZINONE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-03-12 | — | — | EP | disclosed |