Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067618 | 0.80 | PKM (0.51) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL4287111 | 0.78 | MAPK1 (0.59) | KMT2AMEN1MAPK1L3MBTL1NPC1 | |
| SCHEMBL13889647 | 0.77 | NPC1 (0.60) | KMT2AMEN1MAPK1L3MBTL1NPC1 | |
| SCHEMBL4073987 | 0.76 | NPC1 (0.64) | KMT2AMEN1MAPK1L3MBTL1NPC1 | |
| SCHEMBL4064579 | 0.76 | NPC1 (0.58) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL19750331 | 0.75 | MEN1 (0.64) | KMT2AMEN1MAPK1L3MBTL1NPC1 | |
| SCHEMBL5529256 | 0.74 | ATM (0.56) | KMT2AMEN1MAPK1L3MBTL1NPC1 | |
| SCHEMBL5524502 | 0.73 | ALOX5 (0.37) | KMT2ACA12CA9HPGD | |
| SCHEMBL4070760 | 0.72 | RAB9A (0.64) | KMT2AMEN1L3MBTL1NPC1RAB9A | |
| SCHEMBL16894163 | 0.72 | MAPK1 (0.59) | KMT2AMEN1MAPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |