Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064662 | 0.89 | ALDH1A1 (0.45) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL4064747 | 0.81 | KDM4E (0.42) | DRD1ADRB1RXRAGRIN1GRIN2B | |
| SCHEMBL7074380 | 0.80 | ADRB1 (0.61) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL4067061 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KMT2AHTTMEN1LMNA | |
| Hydrochloric Acid SCHEMBL7076503 | 0.79 | ADRB1 (0.59) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL7373758 | 0.75 | L3MBTL1 (0.48) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL1266241 | 0.75 | HTR3E (0.63) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL28816944 | 0.74 | KCNA5 (0.48) | ALDH1A1MAP4K1CHRM4LCATL3MBTL1 | |
| SCHEMBL8257274 | 0.74 | GFER (0.58) | ALDH1A1KMT2AHTTMEN1LMNA | |
| SCHEMBL31381181 | 0.73 | FFAR4 (0.55) | ALDH1A1KMT2AHTTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781257-A | Piperidinylpyrazolopyridine derivative | DAIICHI SANKYO CO LTD | 2015-07-15 | — | — | CN | disclosed |
| EP-1415986-B1 | SPIRO ISOBENZOFURANES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-7205417-B2 | Spiro compounds | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |