Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL4081062 | 0.91 | SIGMAR1 (0.39) | SSTR4SSTR1KMT2AMEN1ALDH1A1 | |
| Butane SCHEMBL4074088 | 0.87 | MEN1 (0.38) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL209344 | 0.83 | ALDH1A1 (0.42) | SSTR4SSTR1KMT2AMEN1GAA | |
| SCHEMBL5161290 | 0.83 | SSTR4 (0.42) | SSTR4SSTR1KMT2AMEN1GAA | |
| SCHEMBL206628 | 0.82 | SSTR4 (0.42) | SSTR4SSTR1KMT2AMEN1GAA | |
| SCHEMBL4074159 | 0.82 | SSTR4 (0.39) | SSTR4SSTR1KMT2AMEN1MAPT | |
| SCHEMBL205833 | 0.77 | KMT2A (0.53) | KMT2AMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL206665 | 0.76 | SSTR4 (0.45) | SSTR4SSTR1KMT2AMEN1MAPT | |
| SCHEMBL5157976 | 0.76 | SSTR4 (0.45) | SSTR4SSTR1KMT2AMEN1NPC1 | |
| SCHEMBL2987319 | 0.75 | MEN1 (0.47) | SSTR4SSTR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |