Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081068 | 0.91 | THRB (0.39) | SSTR4SSTR1KMT2ATSHRMEN1 | |
| SCHEMBL206628 | 0.89 | SSTR4 (0.42) | SSTR4SSTR1KMT2ATSHRNPSR1 | |
| SCHEMBL4074093 | 0.87 | MEN1 (0.38) | KMT2ANPSR1MEN1ALDH1A1MAPT | |
| SCHEMBL209344 | 0.84 | ALDH1A1 (0.42) | SSTR4SSTR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL5161290 | 0.84 | SSTR4 (0.42) | SSTR4SSTR1KMT2ATSHRNPSR1 | |
| Butane SCHEMBL4074157 | 0.82 | SSTR4 (0.40) | SSTR4SSTR1KMT2ATSHRNPSR1 | |
| SCHEMBL205569 | 0.80 | ENPP2 (0.46) | SSTR4SSTR1KMT2ATSHRMEN1 | |
| SCHEMBL204623 | 0.77 | KMT2A (0.48) | SSTR4SSTR1KMT2ATSHRNPSR1 | |
| SCHEMBL5157976 | 0.76 | SSTR4 (0.45) | SSTR4SSTR1KMT2ATSHRNPSR1 | |
| SCHEMBL206665 | 0.76 | SSTR4 (0.45) | SSTR4SSTR1KMT2ATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |