SCHEMBL4074263

SCHEMBL4074263

C=Cc1ccc(C(F)(F)F)c(C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453534 0.81 NFKB1 (0.39)
SCHEMBL3250664 0.78 ERN1 (0.38) APP
SCHEMBL5795608 0.78 POLB (0.36)
SCHEMBL7115432 0.77 ESR1 (0.33) APP
SCHEMBL16958175 0.75 ALDH1A1 (0.41)
SCHEMBL21384829 0.74 PDE2A (0.35) APP
SCHEMBL3244584 0.70 HSD11B1 (0.30)
SCHEMBL3871695 0.69
SCHEMBL21244242 0.69 ESR1 (0.30)
SCHEMBL29446986 0.68 NFKB1 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019120-B1 BLOCK COPOLYMERS NIPPON SODA CO (JP) 2016-04-13 EP disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed