SCHEMBL453534

SCHEMBL453534

C=Cc1cccc(C(F)(F)F)c1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.39
HSD11B1 P28845 1/20 0.37
GRIN2D O15399 2/20 0.36
GRIN3B O60391 2/20 0.36
GRIN1 Q05586 2/20 0.36
GRIN2A Q12879 2/20 0.36
GRIN2B Q13224 2/20 0.36
GRIN2C Q14957 2/20 0.36
GRIN3A Q8TCU5 2/20 0.36
ALDH1A1 P00352 2/20 0.35
AXL P30530 1/20 0.35
TNF P01375 1/20 0.35
IL6 P05231 1/20 0.35
MAOB P27338 5/20 0.33
P4HB P07237 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
LMNA P02545 1/20 0.32
KIF11 P52732 1/20 0.32
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16958175 0.87 ALDH1A1 (0.41) NFKB1ALDH1A1
SCHEMBL4074263 0.81 APP (0.31)
SCHEMBL29446986 0.80 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL165004 0.80 NFKB1 (0.52) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5963736 0.79 NFKB1 (0.39) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL28332824 0.79 NFE2L2 (0.38) ALDH1A1
SCHEMBL1600817 0.79 PIM1 (0.43) NFKB1HSD11B1GRIN2DGRIN3BGRIN1
SCHEMBL25090393 0.78 P2RX7 (0.44) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7031301 0.78 NFKB1 (0.42) NFKB1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7031294 0.78 ERN1 (0.36) NFKB1ALDH1A1LMNAPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN claimed
CN-119819370-A Preparation method of photocatalytic degradation material for treating acid chrome blue K sewage 北方工业大学 2025-04-15 CN disclosed
US-20240124632-A1 Method for Producing Fluorine-Containing Polymer and Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2024-04-18 US disclosed
US-20240043593-A1 Fluorine-Containing Polymer CENTRAL GLASS COMPANY, LIMITED (JP) 2024-02-08 US disclosed
CN-116848162-A Fluorine-containing polymer 中央硝子株式会社 2023-10-03 CN disclosed
CN-116694256-A Special resin adhesive for vehicle-gauge-level power soft-package tab and preparation method thereof 浙江文壹先端新材料有限公司 2023-09-05 CN disclosed
CN-112585113-B Process for distillative purification of fluorine-containing polymerizable monomers 中央硝子株式会社 2023-08-22 CN disclosed
CN-116615410-A Method for producing fluorine-containing polymer and composition 中央硝子株式会社 2023-08-18 CN disclosed
US-20230159766-A1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230159766-A1 CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-8193285-B2 Block copolymers NIPPON SODA CO., LTD. (JP) 2012-06-05 US disclosed
CN-102449000-A Fluorine-containing compound, fluorine-containing polymer compound, resist composition, top coat composition and pattern formation method CENTRAL GLASS CO LTD 2012-05-09 CN disclosed
US-20120077126-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer Compound, Resist Composition, Top Coat Composition And Pattern Formation Method CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-29 US disclosed
US-20120064459-A1 Water Repellent Additive for Immersion Resist CENTRAL GLASS COMPANY, LIMITED (JP) 2012-03-15 US disclosed
US-20120040294-A1 Top Coating Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2012-02-16 US disclosed
US-20110245395-A1 Top Coat Composition CENTRAL GLASS COMPANY, LIMITED 2011-10-06 US disclosed
US-20110244188-A1 Polymerizable Fluoromonomer, Fluoropolymer, Resist Material, and Method of Pattern Formation Central Glass Company , Limited (JP) 2011-10-06 US disclosed
US-20090253867-A1 BLOCK COPOLYMERS NIPPON SODA CO., LTD. (JP) 2009-10-08 US disclosed
EP-2019120-A1 BLOCK COPOLYMERS Nippon Soda Co., Ltd. (JP) 2009-01-28 EP disclosed
WO-1998000750-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DISPLAY DEVICE WITH THE USE OF THE SAME HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO. KG (DE) 1998-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110244188-A1 Polymerizable Fluoromonomer, Fluoropolymer, Resist Material, and Method of Pattern Formation AFF1, FRG1, AFF2 NFKB1 4145/4885HSD11B1 4170/4885GRIN2D 86/4885
US-20120077126-A1 Fluorine-Containing Compound, Fluorine-Containing Polymer Compound, Resist Composition, Top Coat Composition And Pattern Formation Method FRG1, AFF2, FBXL19 NFKB1 4274/4885HSD11B1 4483/4885GRIN2D 770/4885
US-20240124632-A1 Method for Producing Fluorine-Containing Polymer and Composition PFAS, AFF2, AFF1 NFKB1 4144/4885HSD11B1 1754/4885GRIN2D 1543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.