Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | WRN | Q14191 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19059392 | 0.82 | BCL2A1 (0.32) | BLMWRNALDH1A1KDM4EHPGD | |
| SCHEMBL13731395 | 0.80 | PTGS2 (0.32) | BLMWRNALDH1A1KDM4EHPGD | |
| SCHEMBL6850987 | 0.76 | GSK3A (0.44) | ALDH1A1KDM4EHPGDCES1MEN1 | |
| SCHEMBL13732723 | 0.76 | KMT2A (0.44) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1297932 | 0.74 | CASP3 (0.30) | CASP3 | |
| SCHEMBL10919684 | 0.74 | L3MBTL1 (0.36) | BLMALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL17962594 | 0.67 | BLM (0.50) | BLMWRNALDH1A1KDM4EHPGD | |
| SCHEMBL802733 | 0.67 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTGSK3A | |
| SCHEMBL19370217 | 0.66 | CASP3 (0.33) | CASP3 | |
| SCHEMBL20756369 | 0.66 | MEN1 (0.48) | BLMALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432250-B | Indoles [2,3-a] pyrroles [3,4-c] carbazole -5,7- diketone -6- (thiosemicarbazone) compounds with active anticancer and its preparation method and application | 河南师范大学 | 2018-07-10 | — | — | CN | claimed |
| CN-106478643-B | Indoles [2,3-a] pyrroles [3,4-c] carbazole -5,7- diketone -6- virtue hydrazone compounds and preparation method thereof and the application in anticancer drug | 河南师范大学 | 2018-07-10 | — | — | CN | claimed |
| CN-106478643-A | Fragrant hydrazone compounds of indole [2,3 a] pyrroles [3,4 c] carbazole 5,7 diketone 6 and preparation method thereof and the application in cancer therapy drug | 河南师范大学 | 2017-03-08 | — | — | CN | claimed |
| CN-106432250-A | Indole [2,3-a] pyrrole[3,4-c] carbazole-5,7-diketone-6-thiosemicarbazone compounds with antitumor activity as well as preparation method and application of compounds | 河南师范大学 | 2017-02-22 | — | — | CN | claimed |
| US-8840769-B2 | Resin composition containing catalyst precursor for electroless plating in forming electro-magnetic shielding layer, method of forming metallic pattern using the same, and metallic pattern formed by the same method | LG CHEM, LTD. (KR) | 2014-09-23 | — | — | US | claimed |
| US-20140030426-A1 | RESIN COMPOSITION CONTAINING CATALYST PRECURSOR FOR ELECTROLESS PLATING IN FORMING ELECTRO-MAGNETIC SHIELDING LAYER, METHOD OF FORMING METALLIC PATTERN USING THE SAME, AND METALLIC PATTERN FORMED BY THE SAME METHOD | LG CHEM, LTD. (KR) | 2014-01-30 | — | — | US | claimed |
| US-8519017-B2 | Resin composition containing catalyst precursor for electroless plating in forming electro-magnetic shielding layer, method of forming metallic pattern using the same, and metallic pattern formed by the same method | LG CHEM, LTD. (KR) | 2013-08-27 | — | — | US | claimed |
| US-20100167081-A1 | RESIN COMPOSITION CONTAINING CATALYST PRECURSOR FOR ELECTROLESS PLATING IN FORMING ELECTRO-MAGNETIC SHIELDING LAYER, METHOD OF FORMING METALLIC PATTERN USING THE SAME, AND METALLIC PATTERN FORMED BY THE SAME METHOD | LG CHEM, LTD. (KR) | 2010-07-01 | — | — | US | claimed |
| JP-57120502-A | — | — | None | — | — | JP | disclosed |
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |
| EP-2953457-B1 | ERK INHIBITORS AND USES THEREOF | CELGENE CAR LLC (BM) | 2020-04-08 | — | — | EP | disclosed |
| EP-3549934-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2019-10-09 | — | — | EP | disclosed |
| CN-106432250-B | Indoles [2,3-a] pyrroles [3,4-c] carbazole -5,7- diketone -6- (thiosemicarbazone) compounds with active anticancer and its preparation method and application | 河南师范大学 | 2018-07-10 | — | — | CN | disclosed |
| CN-106478643-B | Indoles [2,3-a] pyrroles [3,4-c] carbazole -5,7- diketone -6- virtue hydrazone compounds and preparation method thereof and the application in anticancer drug | 河南师范大学 | 2018-07-10 | — | — | CN | disclosed |
| EP-0657411-A1 | Improved synthesis of bisindolylmaleimides | ELI LILLY AND COMPANY (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0630241-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| EP-0630242-A1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018766-A1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |
| WO-1993018765-A1 | INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-30 | — | — | WO | disclosed |
| JP-S57120502-A | INSECTICIDE | MITSUBISHI CHEM IND LTD | 1982-07-27 | — | — | JP | disclosed |