Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079705 | 0.84 | SMN1; SMN2 (0.47) | NPC1GAATPSAB1KMT2AL3MBTL1 | |
| SCHEMBL4075832 | 0.82 | GAA (0.64) | LMNANPC1GAATPSAB1MAPT | |
| SCHEMBL4075831 | 0.77 | GAA (0.61) | LMNANPC1GAATPSAB1MAPT | |
| SCHEMBL17372432 | 0.71 | NPC1 (0.57) | LMNANPC1GAAMAPTRXFP1 | |
| SCHEMBL17570500 | 0.71 | AOC3 (0.65) | LMNANPC1TPSAB1MAPTF10 | |
| SCHEMBL17785699 | 0.71 | LMNA (0.55) | LMNANPC1MAPTEPHX2 | |
| SCHEMBL24499495 | 0.69 | NPC1 (0.61) | LMNANPC1MAPTF10F7 | |
| SCHEMBL6290206 | 0.69 | NPC1 (0.61) | LMNANPC1MAPTF10F7 | |
| SCHEMBL6290205 | 0.69 | NPC1 (0.61) | LMNANPC1MAPTF10F7 | |
| SCHEMBL10690766 | 0.69 | ALDH1A1 (0.55) | LMNAGAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |