SCHEMBL4076137

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4080470	0.90	ALOX5 (0.82)	ALOX5MAPTKCNH2GRM2HPGD
	Setileuton SCHEMBL29371714	0.89	ALOX5 (1.00)	ALOX5KCNH2GRM2HPGDALDH1A1
	Setileuton SCHEMBL1528741	0.89	ALOX5 (1.00)	ALOX5KCNH2GRM2HPGDALDH1A1
	Setileuton SCHEMBL13691961	0.89	ALOX5 (1.00)	ALOX5KCNH2GRM2HPGDALDH1A1
	Setileuton SCHEMBL1528740	0.89	ALOX5 (1.00)	ALOX5KCNH2GRM2HPGDALDH1A1
	SCHEMBL15275058	0.89	ALOX5 (0.81)	ALOX5MAPTKCNH2GRM2HPGD
	SCHEMBL4078770	0.89	ALOX5 (0.81)	ALOX5MAPTKCNH2GRM2HPGD
	SCHEMBL13799549	0.89	ALOX5 (0.81)	ALOX5KCNH2GRM2HPGDALDH1A1
	SCHEMBL4087806	0.87	ALOX5 (0.81)	ALOX5KCNH2GRM2HPGDALDH1A1
	SCHEMBL4076133	0.87	ALOX5 (0.81)	ALOX5KCNH2GRM2HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.