Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL7947125 | 1.00 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL28291481 | 0.95 | ALDH1A1 (0.73) | — | |
| Tetrahydrofuran SCHEMBL1005228 | 0.95 | ALDH1A1 (0.89) | — | |
| Tetrahydrofuran SCHEMBL1512532 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL2177525 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL29711634 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL21496006 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL1278401 | 0.90 | — | — | |
| Tetrahydrofuran SCHEMBL4444183 | 0.90 | ALDH1A1 (0.80) | — | |
| Tetrahydrofuran SCHEMBL22230565 | 0.90 | ALDH1A1 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11745216-B2 | Method for producing film | JSR CORPORATION (JP) | 2023-09-05 | — | — | US | disclosed |
| US-20230027151-A1 | METHOD FOR PRODUCING FILM | JSR CORPORATION (JP) | 2023-01-26 | — | — | US | disclosed |
| WO-2020022128-A1 | ORGANIC POLYMER, METHOD FOR PRODUCING SAME AND USE OF SAME | 国立大学法人東京大学 | 2020-01-30 | — | — | WO | disclosed |
| US-20190112417-A1 | NOVEL ORGANIC POLYMER AND METHOD FOR PRODUCING SAME | THE UNIVERSITY OF TOKYO (JP) | 2019-04-18 | — | — | US | disclosed |
| EP-3438150-A1 | NOVEL ORGANIC POLYMER AND METHOD FOR PRODUCING SAME | THE UNIVERSITY OF TOKYO (JP) | 2019-02-06 | — | — | EP | disclosed |
| CN-109071783-A | Novel organic polymer and its manufacturing method | 国立大学法人东京大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-106928091-B | Fluorochemical and its synthetic method | 南开大学 | 2018-12-04 | — | — | CN | disclosed |
| EP-2019120-B1 | BLOCK COPOLYMERS | NIPPON SODA CO (JP) | 2016-04-13 | — | — | EP | disclosed |
| CN-103478142-B | The method of control of microbicide compositions and plant disease | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2016-03-30 | — | — | CN | disclosed |
| CN-101215260-B | Method for preparing benzoylpyridine derivatices and salt thereof | ISHIHARA SANGYO KAISHA | 2014-07-09 | — | — | CN | disclosed |
| CN-101443371-B | Block copolymers | NIPPON SODA CO | 2011-09-07 | — | — | CN | disclosed |
| CN-102165961-A | Bactericide composition and method of controlling plant disease | ISHIHARA SANGYO KAISHA | 2011-08-31 | — | — | CN | disclosed |
| CN-101822253-A | The method of control of microbicide compositions and plant disease | ISHIHARA SANGYO KAISHA | 2010-09-08 | — | — | CN | disclosed |
| CN-100581362-C | Bactericide composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA | 2010-01-20 | — | — | CN | disclosed |
| US-20090253867-A1 | BLOCK COPOLYMERS | NIPPON SODA CO., LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
| CN-101443371-A | Block copolymers | NIPPON SODA CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| EP-2019120-A1 | BLOCK COPOLYMERS | Nippon Soda Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |
| CN-101215260-A | Method for preparing benzoylpyridine derivatices and salt thereof | ISHIHARA SANGYO KAISHA (JP) | 2008-07-09 | — | — | CN | disclosed |
| CN-101199274-A | Bactericide composition and method for controlling plant disease | ISHIHARA SANGYO KAISHA (JP) | 2008-06-18 | — | — | CN | disclosed |
| CN-1874680-A | bactericide composition and method for controlling plant diseases | ISHIHARA SANGYO KAISHA (JP) | 2006-12-06 | — | — | CN | disclosed |