SCHEMBL4076513

SCHEMBL4076513

C=CC(=O)N(C)Cc1cc2ccccc2c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.39
EGFR P00533 2/20 0.39
ITK Q08881 2/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
CYP1A2 P05177 2/20 0.37
TSHR P16473 1/20 0.36
FAAH O00519 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
DHODH Q02127 1/20 0.35
TRPM4 Q8TD43 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079687 0.82 CYP1A2 (0.56) ALDH1A1MAPTKDM4EATMCYP1A2
SCHEMBL4079512 0.80 ALDH1A1 (0.42) ALDH1A1HPGDMAPTKDM4EATM
SCHEMBL4076336 0.76 KMT2A (0.47) PSMB5EGFRITKALDH1A1HPGD
SCHEMBL8383231 0.74 HSP90AA1 (0.48) EGFRITKALDH1A1HPGDMAPT
SCHEMBL4089366 0.74 PSMB5 (0.57) PSMB5EGFRITKALDH1A1HPGD
SCHEMBL1093068 0.73 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2
SCHEMBL1093103 0.73 ALDH1A1 (0.59) ALDH1A1HPGDMAPTKDM4ETSHR
SCHEMBL1092315 0.72 LMNA (0.52) HPGDMAPTKDM4ESMN1; SMN2
SCHEMBL25463757 0.72 TSHR (0.58) ALDH1A1HPGDMAPTKDM4EATM
SCHEMBL491378 0.72 NPC1 (0.65) EGFRITKALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7500895-B2 Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORPORATION (JP) 2009-03-10 US disclosed
US-20060127563-A1 Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORPORATION (JP) 2006-06-15 US disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 US disclosed
CN-1713787-A Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORP (JP) 2005-12-28 CN disclosed