SCHEMBL4089366

SCHEMBL4089366

C=CC(=O)N(C)Cc1ccc2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.57
EGFR P00533 4/20 0.47
ITK Q08881 2/20 0.47
PYCR1 P32322 1/20 0.47
ACHE P22303 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
JAK1 P23458 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22454608 0.82 MC4R (0.47) PSMB5EGFRKDM4EMEN1ALDH1A1
SCHEMBL19472466 0.82 EGFR (0.50) EGFRITKPYCR1KDM4EALDH1A1
SCHEMBL6417278 0.81 PDPK1 (0.49) PYCR1ACHEKDM4EALDH1A1TRPV1
SCHEMBL6417280 0.81 PDPK1 (0.49) PYCR1ACHEKDM4EALDH1A1TRPV1
SCHEMBL23972322 0.81 SLC6A2 (0.55) PYCR1ACHEMEN1ALDH1A1MAPT
SCHEMBL491378 0.80 NPC1 (0.65) EGFRITKMEN1ALDH1A1HPGD
SCHEMBL10397484 0.80 PYCR1 (0.50) PYCR1ACHEMEN1KMT2ATRPV1
SCHEMBL29565966 0.78 SLC6A2 (0.56) PYCR1ACHEMEN1KMT2ATRPV1
SCHEMBL26027596 0.77 TRPV1 (0.51) PYCR1ACHEMEN1HPGDKMT2A
SCHEMBL23227079 0.76 ALDH1A1 (0.54) EGFRITKPYCR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7500895-B2 Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORPORATION (JP) 2009-03-10 US disclosed
US-20060127563-A1 Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device SEIKO EPSON CORPORATION (JP) 2006-06-15 US disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 US disclosed