SCHEMBL4076791

SCHEMBL4076791

CO[Si](CBr)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CA4 P22748 1/20 0.33
MAPT P10636 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
LTA4H P09960 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL647836 0.81 CA4 (0.36) ALDH1A1TSHRCA4MAPTESR1
SCHEMBL647415 0.81 CA4 (0.36) ALDH1A1TSHRCA4MAPTESR1
SCHEMBL705542 0.79 CA4 (0.35) ALDH1A1CA4ESR1ESR2LTA4H
SCHEMBL4082788 0.78 LTA4H (0.32) TRPA1ALDH1A1TSHRMAPTLTA4H
SCHEMBL4079195 0.77 CA4 (0.33) ALDH1A1CA4ESR1ESR2LTA4H
SCHEMBL15912070 0.77 ESR1 (0.35) TRPA1ALDH1A1TSHRCA4MAPT
SCHEMBL1263393 0.77 TRPA1 (0.33) TRPA1ALDH1A1TSHRCA4MAPT
SCHEMBL1262887 0.77 CA4 (0.33) CA4ESR1ESR2LTA4HPOLB
SCHEMBL703898 0.77 CA4 (0.33) CA4ESR1ESR2LTA4HPOLB
SCHEMBL27996306 0.77 CA4 (0.35) CA4ESR1ESR2LTA4HPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed