Diclosulam

Diclosulam

SCHEMBL407709

CCOc1nc(F)cc2nc(S(=O)(=O)Nc3c(Cl)cccc3Cl)nn12.COc1ncc(F)c2nc(S(=O)(=O)Nc3c(F)cccc3F)nn12

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 5/20 0.33
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
PIK3CG P48736 1/20 0.31
EIF2AK3 Q9NZJ5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8848572 0.88 GNRHR (0.34) CCR4
Diclosulam SCHEMBL116344 0.87 GNRHR (0.35) CCR4
SCHEMBL6244148 0.85 CCR4 (0.39) CCR4
SCHEMBL6999983 0.85 TSHR (0.36)
SCHEMBL8113170 0.83 TSHR (0.39) CCR4
SCHEMBL910274 0.82 GAA (0.42) CCR4
Florasulam SCHEMBL18955499 0.82 GAA (0.39) CCR4PIK3CDPIK3CAPIK3CBPIK3CG
Florasulam SCHEMBL116614 0.82 GAA (0.39) CCR4PIK3CDPIK3CAPIK3CBPIK3CG
Diclosulam SCHEMBL2231960 0.80 CA2 (0.33)
SCHEMBL26838562 0.80 CCR4 (0.34) CCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1536685-B1 PROCESS FOR PREPARING PASTE-EXTRUDED SULFONAMIDE COMPOSITIONS DU PONT (US) 2006-04-12 EP claimed
EP-2376219-B1 METHOD FOR CONTROLLING WATER EVAPORATION UNIV MELBOURNE (AU) 2018-03-14 EP disclosed
US-8696987-B2 Method for controlling water evaporation POLYMERS CRC LTD (AU) 2014-04-15 US disclosed
US-20120018387-A1 METHOD FOR CONTROLLING WATER EVAPORATION POLYMERS CRC LTD (AU) 2012-01-26 US disclosed
EP-2376219-A1 METHOD FOR CONTROLLING WATER EVAPORATION Polymers CRC Limited (AU) 2011-10-19 EP disclosed
WO-2010071931-A1 METHOD FOR CONTROLLING WATER EVAPORATION POLYMERS CRC LTD (AU) 2010-07-01 WO disclosed