Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848572 | 0.93 | GNRHR (0.34) | TSHRKDM4EALDH1A1GNRHR | |
| SCHEMBL8848603 | 0.90 | WDR5 (0.42) | ALDH1A1GAAKMT2AWDR5 | |
| Diclosulam SCHEMBL116344 | 0.89 | GNRHR (0.35) | TSHRALDH1A1SMN1; SMN2GNRHR | |
| SCHEMBL910274 | 0.88 | GAA (0.42) | TSHRGAAMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9176684 | 0.85 | ALDH1A1 (0.38) | TSHRKDM4EALDH1A1GAAKMT2A | |
| Diclosulam SCHEMBL407709 | 0.85 | CCR4 (0.33) | — | |
| SCHEMBL4890265 | 0.83 | WDR5 (0.39) | ALDH1A1SMN1; SMN2WDR5 | |
| SCHEMBL118467 | 0.83 | WDR5 (0.39) | ALDH1A1SMN1; SMN2WDR5 | |
| SCHEMBL8111633 | 0.83 | SCN9A (0.35) | TSHRKDM4EALDH1A1 | |
| SCHEMBL29396759 | 0.83 | WDR5 (0.39) | ALDH1A1SMN1; SMN2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066289-B1 | PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2003-11-19 | — | — | EP | disclosed |