SCHEMBL40774

SCHEMBL40774

COCCOCCOCCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 1/20 0.46
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA9 Q16790 2/20 0.45
GAA P10253 1/20 0.41
STAT3 P40763 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 1/20 0.39
PSMD10 O75832 1/20 0.39
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA7 P43166 1/20 0.38
CA5B Q9Y2D0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19003422 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL18998977 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL2329512 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL1218220 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL361530 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL25398474 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL8282614 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL22262524 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL21877144 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12
SCHEMBL13169282 1.00 ALDH1A1 (0.47) ALDH1A1LMNAHPGDHTTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 565 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113248352-B Method for synthesizing heptaglyme through solid phase 长沙创新药物工业技术研究院有限公司 2024-08-13 CN claimed
CN-117327299-A Graphene oxide-based temperature-sensitive composite hydrogel and preparation method and application thereof 同济大学 2024-01-02 CN claimed
CN-116891476-A Fluorescent probe for rapidly detecting hydrogen sulfide gas and preparation method and application thereof 云南电力试验研究院(集团)有限公司 2023-10-17 CN claimed
CN-112174785-B Fluorescent probe based on tetraphenylethylene derivative, preparation method and application thereof 扬州大学 2022-03-29 CN claimed
CN-113248352-A Method for solid-phase synthesis of heptaethylene glycol monomethyl ether 湖南华腾制药有限公司 2021-08-13 CN claimed
CN-112174785-A Fluorescent probe based on tetraphenylethylene derivative, preparation method and application thereof 扬州大学 2021-01-05 CN claimed
EP-3524638-B1 AMINOSILANE-BASED COMPOUND, PROCESS FOR PREPARING SAME, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPRISING SAME LG CHEMICAL LTD (KR) 2020-06-17 EP claimed
CN-110734450-A hydrogen sulfide fluorescent probes and preparation method and application thereof 贺州学院 2020-01-31 CN claimed
CN-104177393-A Photosensitizer, and preparation method and application thereof SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO LTD 2014-12-03 CN claimed
US-20260077069-A1 COMBINATIONS OF CONTRAST AGENTS BAYER AG (DE) 2026-03-19 US disclosed
EP-4692071-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
US-12540278-B2 Temperature programmable small molecules for thermoresponsive smart windows and applications thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2026-02-03 US disclosed
US-12508251-B2 CD4 mimic compound with anti-HIV activity NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY; (JP) 2025-12-30 US disclosed
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2025-10-09 US disclosed
WO-1993020078-A1 PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES THE UPJOHN COMPANY (US) 1993-10-14 WO disclosed
WO-1993009088-A1 IMPROVED METHOD FOR SYNTHESIS OF DESFERRIOXAMINE B, ANALOGS AND HOMOLOGS THEREOF UNIVERSITY OF FLORIDA (US) 1993-05-13 WO disclosed
EP-0519996-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1992-12-30 EP disclosed
WO-1991013876-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1991-09-19 WO disclosed
EP-0337714-A2 HIV protease inhibitors useful for the treatment of aids MERCK & CO. INC. (US) 1989-10-18 EP disclosed
US-4436664-A PHASE TRANSFER AGENTS W. R. GRACE & CO. (US) 1984-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260077069-A1 COMBINATIONS OF CONTRAST AGENTS GBA1, GBA3, GLS2 ALDH1A1 3682/4885LMNA 431/4885HPGD 1941/4885
US-12508251-B2 CD4 mimic compound with anti-HIV activity CD4, CD81, SLC11A2 ALDH1A1 1615/4885LMNA 4562/4885HPGD 3528/4885
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 ALDH1A1 641/4885LMNA 420/4885HPGD 4461/4885
US-12540278-B2 Temperature programmable small molecules for thermoresponsive smart windows and applications thereof CRY1, C1S, CRY2 ALDH1A1 309/4885LMNA 946/4885HPGD 3480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.