Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003422 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL18998977 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL2329512 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL1218220 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL40774 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL25398474 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL8282614 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL22262524 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL21877144 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 | |
| SCHEMBL13169282 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAHPGDHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000983-A1 | METHODS AND COMPOSITIONS FOR SYNTHESIS OF TWO-PHOTON CLEAVABLE PHOSPHORAMIDITE MOLECULES FOR OLIGONUCLEOTIDE CONJUGATION | CITY UNIVERSITY OF HONG KONG (HK) | 2023-01-05 | — | — | US | claimed |
| CN-108299498-B | Quaternary phosphonium salt with p-toluenesulfonate as anion and synthesis method, preparation method and application thereof | 暨南大学 | 2020-06-16 | — | — | CN | claimed |
| CN-101831054-B | Method for distinguishing fungi and bacteria | CHINESE ACAD INST CHEMISTRY | 2011-11-16 | — | — | CN | claimed |
| CN-101831054-A | Method for distinguishing fungi and bacteria | CHINESE ACAD INST CHEMISTRY | 2010-09-15 | — | — | CN | claimed |
| US-20250313572-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2025-10-09 | — | — | US | disclosed |
| US-12435060-B2 | Acylamino bridged heterocyclic compound, and composition and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2025-10-07 | — | — | US | disclosed |
| US-20250019351-A1 | COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2025-01-16 | — | — | US | disclosed |
| US-20240360088-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2024-10-31 | — | — | US | disclosed |
| US-12077512-B2 | Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-09-03 | — | — | US | disclosed |
| US-20240228509-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2024-07-11 | — | — | US | disclosed |
| EP-4367104-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | Oregon Health & Science University (US) | 2024-05-15 | — | — | EP | disclosed |
| US-20240139164-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-02 | — | — | US | disclosed |
| EP-0349748-A1 | Substituted N-aryl-nitrogen containing heterocycles | BAYER AG (DE) | 1990-01-10 | — | — | EP | disclosed |
| EP-0146269-B1 | HETERO-POLYCYCLIC AROMATIC COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-03 | — | — | EP | disclosed |
| US-4719296-A | PHOTOCHROMISM | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-01-12 | — | — | US | disclosed |
| US-4650882-A | Dyes having two 5-membered lactone rings fused to a central cyclohexa-1.4-diene nucleus | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-03-17 | — | — | US | disclosed |
| EP-0146269-A2 | Hetero-polycyclic aromatic compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-26 | — | — | EP | disclosed |
| US-4436664-A | PHASE TRANSFER AGENTS | W. R. GRACE & CO. (US) | 1984-03-13 | — | — | US | disclosed |
| US-4018832-A | Novel complexing agents derived from cyclotriveratrylene | EASTMAN KODAK COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4001279-A | CARRY INSOLUBLE REAGENT SUBSTANCES INTO SOLUTION IN NON-HYDROXYLIC MEDIA; CROWN COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228509-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | MCL1, BCL2A1, BCL2L10 | ALDH1A1 641/4885LMNA 420/4885HPGD 4461/4885 |
| US-20240139164-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | RICTOR, MTOR, RPTOR | ALDH1A1 4627/4885LMNA 3835/4885HPGD 3013/4885 |
| US-20230000983-A1 | METHODS AND COMPOSITIONS FOR SYNTHESIS OF TWO-PHOTON CLEAVABLE PHOSPHORAMIDITE MOLECULES FOR OLIGONUCLEOTIDE CONJUGATION | PCNA, POLB, NCL | ALDH1A1 4749/4885LMNA 553/4885HPGD 3818/4885 |
| US-20250313572-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | MCL1, BCL2A1, BCL2L10 | ALDH1A1 641/4885LMNA 420/4885HPGD 4461/4885 |
| US-12077512-B2 | Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment | GABBR1, GABBR2, PMP22 | ALDH1A1 2517/4885LMNA 3058/4885HPGD 3913/4885 |
| US-20240360088-A1 | WATER-SOLUBLE NERVE DYES FOR IN VIVO NERVE-SPECIFIC IMAGING | PAX8, GAP43, PAX2 | ALDH1A1 1457/4885LMNA 1129/4885HPGD 1476/4885 |
| US-20250019351-A1 | COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT | GABBR1, GABBR2, PMP22 | ALDH1A1 2517/4885LMNA 3058/4885HPGD 3913/4885 |
| US-12435060-B2 | Acylamino bridged heterocyclic compound, and composition and application thereof | RIPK1, RIPK3, RIPK4 | ALDH1A1 4164/4885LMNA 2659/4885HPGD 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.