Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA3 | P07451 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL7621993 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL989734 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL371424 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL220600 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL10703973 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL3410087 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL19066603 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL987205 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL4077816 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 | |
| Ethylenediamine SCHEMBL8667785 | 1.00 | NFKB1 (0.33) | NFKB1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468262-A | Reaction product of phenol aldehyde, amine condensate and succinic anhydride bearing polyolefin | TEXACO INC. (US) | 1995-11-21 | — | — | US | claimed |
| CN-117957114-A | Multilayer film, optical multilayer film, and method for producing same | 日本瑞翁株式会社 | 2024-04-30 | — | — | CN | disclosed |
| WO-2024024467-A1 | LIQUID COMPOSITION AND OPTICAL FILM | 日本ゼオン株式会社 | 2024-02-01 | — | — | WO | disclosed |
| WO-2023233958-A1 | MULTILAYER FILM AND METHOD FOR MANUFACTURING SAME, POLARIZING PLATE, AND ORGANIC ELECTROLUMINESCENT IMAGE DISPLAY DEVICE | 日本ゼオン株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2023167184-A1 | NEUTROPHIL DEPLETING MATERIAL AND METHOD FOR PRODUCING NEUTROPHIL DEPLETING MATERIAL | 東レ株式会社 | 2023-09-07 | — | — | WO | disclosed |
| CN-111443415-B | Polarizing plate | 住友化学株式会社 | 2023-08-01 | — | — | CN | disclosed |
| WO-2023054256-A1 | MULTILAYER FILM, OPTICAL MULTILAYER FILM, AND MANUFACTURING METHOD | 日本ゼオン株式会社 | 2023-04-06 | — | — | WO | disclosed |
| CN-114746471-A | Hardener for epoxy casting resins | SIKA技术股份公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110229366-B | Multilayer film and method for producing same | 日本瑞翁株式会社 | 2022-05-06 | — | — | CN | disclosed |
| CN-109562219-B | Material for purifying blood | 东丽株式会社 | 2021-05-18 | — | — | CN | disclosed |
| EP-0158247-A1 | Paper-making auxiliary agent | BAYER AG (DE) | 1985-10-16 | — | — | EP | disclosed |
| US-4384110-A | POLYALKYLENE-AMINES, PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-17 | — | — | US | disclosed |
| US-4348514-A | ACCELERATION OF DRAINAGE IN PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4319019-A | RETENTION AIDS AND DRAINAGE ACCELERATORS IN PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-09 | — | — | US | disclosed |
| EP-0005241-B1 | POLYALKYLENE POLYAMINES CONTAINING QUATERNARY AMMONIUM GROUPS, METHOD FOR THEIR PREPARATION AND THEIR USE AS AUXILIARY AGENTS IN PAPER MAKING | BAYER AG (DE) | 1981-04-01 | — | — | EP | disclosed |
| US-4250299-A | RETENTION AGENTS AND DRAINAGE ACCELERATORS FOR PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
| US-4250298-A | RETENTION AGENTS AND DRAINAGE ACCELERATORS FOR PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
| US-4250112-A | PAPERMAKING | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |
| EP-0005241-A1 | Polyalkylene polyamines containing quaternary ammonium groups, method for their preparation and their use as auxiliary agents in paper making | BAYER AG (DE) | 1979-11-14 | — | — | EP | disclosed |
| US-3941834-A | DETERGENT, ANTIDEPOSIT, VISCOSITY IMPROVER FOR LUBRICATING OIL | STANDARD OIL COMPANY (US) | 1976-03-02 | — | — | US | disclosed |