SCHEMBL4077832

SCHEMBL4077832

CCO[Si](CCl)(CCc1ccccc1)CCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
TP53 P04637 1/20 0.35
RAB9A P51151 3/20 0.35
NPC1 O15118 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CASP1 P29466 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TAAR1 Q96RJ0 3/20 0.34
ATM Q13315 1/20 0.34
KCNH2 Q12809 2/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17750059 0.89 TDP1 (0.43) TDP1TP53RAB9ANPC1SMN1; SMN2
SCHEMBL4084761 0.86 RAB9A (0.37) TDP1TP53RAB9ANPC1MEN1
SCHEMBL4076369 0.82 ALDH1A1 (0.43) TDP1TP53RAB9ANPC1SMN1; SMN2
SCHEMBL4077926 0.82 TDP1 (0.42) TDP1TP53RAB9ANPC1SMN1; SMN2
SCHEMBL4077455 0.82 TDP1 (0.38) TDP1TP53RAB9ANPC1MEN1
SCHEMBL4077203 0.81 TDP1 (0.40) TDP1RAB9ANPC1SMN1; SMN2ALDH1A1
SCHEMBL6036860 0.81 TDP1 (0.36) TDP1TP53RAB9ANPC1MEN1
SCHEMBL4077993 0.77 NPC1 (0.38) TDP1RAB9ANPC1KMT2ASMN1; SMN2
SCHEMBL107467 0.77 TDP1 (0.43) TDP1TP53RAB9ANPC1SMN1; SMN2
SCHEMBL9716563 0.77 TDP1 (0.43) TDP1TP53RAB9AKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed