Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 14/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.47 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | PDE8A | O60658 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565600 | 0.91 | SLC29A1 (0.53) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL15065644 | 0.88 | SLC29A1 (0.55) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL141542 | 0.86 | SLC29A1 (0.61) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL4417277 | 0.81 | SLC29A1 (0.47) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL7446848 | 0.79 | SLC29A1 (0.53) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL11045336 | 0.77 | SLC29A1 (0.47) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL2458642 | 0.73 | SLC29A1 (0.46) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL11046569 | 0.73 | TSHR (0.49) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL4077875 | 0.71 | SLC29A1 (0.43) | SLC29A1KDM4EALDH1A1LMNANPSR1 | |
| SCHEMBL11050390 | 0.71 | SLC29A1 (0.38) | SLC29A1ALDH1A1LMNAHIF1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062580-A1 | Use of dipyridamole or mopidamole for treatment and prevention of thromboembolic diseases and disorders caused by excessive formation of thrombin and/or by elevated expression of trombin receptors | Boehringer Ingelheim International GmbH (DE) | 2009-05-27 | — | — | EP | disclosed |