SCHEMBL4417277

SCHEMBL4417277

OCCON(OCCO)c1nc(N2CCCCC2)c2nc(N(OCCO)OCCO)ncc2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 15/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ PDE2A O00408 1/20 0.47
▸ RGS12 O14924 1/20 0.47
▸ SLC22A2 O15244 1/20 0.47
▸ SLC22A1 O15245 1/20 0.47
▸ ABCC4 O15439 1/20 0.47
▸ ABCC5 O15440 1/20 0.47
▸ PDE6D O43924 1/20 0.47
▸ PDE8A O60658 1/20 0.47
▸ GMNN O75496 1/20 0.47
▸ USP2 O75604 1/20 0.47
▸ PDE5A O76074 1/20 0.47
▸ ABCB11 O95342 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ HSP90AA1 P07900 1/20 0.47
▸ CHRM2 P08172 1/20 0.47
▸ ABCB1 P08183 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141542 0.86 SLC29A1 (0.61) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL9565600 0.84 SLC29A1 (0.53) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL4077877 0.81 SLC29A1 (0.47) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL15065644 0.80 SLC29A1 (0.55) SLC29A1KDM4EMEN1PDE2ARGS12
Mopidamol SCHEMBL9440 0.79 SLC29A1 (0.72) SLC29A1KDM4EMEN1PDE2ARGS12
Mopidamol SCHEMBL30179377 0.79 SLC29A1 (0.72) SLC29A1KDM4EMEN1PDE2ARGS12
Mopidamol SCHEMBL29352335 0.79 SLC29A1 (0.72) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL7446848 0.79 SLC29A1 (0.53) SLC29A1KDM4EMEN1PDE2ARGS12
SCHEMBL11852761 0.75 SLC29A1 (0.41) SLC29A1KDM4EMEN1PDE2ARGS12
Hydrochloric Acid SCHEMBL11853330 0.74 SLC29A1 (0.40) SLC29A1KDM4EMEN1PDE2ARGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014392-B1 ANTITHROMBOTIC DRUGS COMBINATION AND PROCESS FOR ITS MANUFACTURE Dr. Karl Thomae GmbH (DE) 1981-11-04 — — EP claimed
JP-2188526-A — — None — — JP disclosed
US-20090326633-A1 CONTROLLED RELEASE ENDOPROSTHETIC DEVICE BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2009-12-31 — — US disclosed
US-20080082156-A1 CONTROLLED RELEASE ENDOPROSTHETIC DEVICE EISERT WOLFGANG 2008-04-03 — — US disclosed
US-20080076786-A1 USE OF RADICAL-SCAVENGING COMPOUNDS FOR TREATMENT AND PREVENTION OF NO-DEPENDENT MICROCIRCULATION DISORDERS EISERT WOLFGANG 2008-03-27 — — US disclosed
US-20070082917-A1 Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders EISERT WOLFGANG 2007-04-12 — — US disclosed
EP-1441667-B1 IMPROVED ENDOPROSTHETIC DEVICE BOEHRINGER INGELHEIM PHARMA (DE) 2007-01-17 — — EP disclosed
US-7064130-B2 Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2006-06-20 — — US disclosed
US-20060128730-A1 Use of radical-scavenging compounds for treatment and prevention of NO-dependent microcirculation disorders BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2006-06-15 — — US disclosed
US-20050282830-A1 Use of dipyridamole or mopidamole for treatment and prevention of MMP-9-dependent disorders BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-12-22 — — US disclosed
US-4997645-A Administering interferon and dipyridamole BOEHRINGER INGELHEIM GMBH (DE) 1991-03-05 — — US disclosed
JP-H02188526-A PHARMACEUTICAL COMPOSITION FOR TREATING TUMOR BOEHRINGER INGELHEIM INTERNATL GMBH 1990-07-24 — — JP disclosed
US-4650664-A INCREASED BIOAVAILABILITY DR. KARL THOMAE GMBH (DE) 1987-03-17 — — US disclosed
US-4596705-A Mopidamol or salt thereof and acid substance in ratio 1:1 DR. KARL THOMAE GMBH (DE) 1986-06-24 — — US disclosed
US-4329346-A ANTILEKEMIC AGENTS BOEHRINGER INGELHEIM GMBH (DE) 1982-05-11 — — US disclosed
US-4329346-A ANTILEKEMIC AGENTS BOEHRINGER INGELHEIM GMBH (DE) 1982-05-11 — — US disclosed
US-4329346-A ANTILEKEMIC AGENTS BOEHRINGER INGELHEIM GMBH (DE) 1982-05-11 — — US disclosed
US-4285945-A SYNERGISTIC MIXTURE OF 2,6-BIS/DIETHANOLAMINO/-4-PIPERIDINO-PYRIMIDO/5,4-D/PYRIMIDINE AND SULFINPYRAZONE SLICHTER SHERRILL J 1981-08-25 — — US disclosed
US-4285945-A SYNERGISTIC MIXTURE OF 2,6-BIS/DIETHANOLAMINO/-4-PIPERIDINO-PYRIMIDO/5,4-D/PYRIMIDINE AND SULFINPYRAZONE SLICHTER SHERRILL J 1981-08-25 — — US disclosed
EP-0019586-A1 Antithrombotic combination formulas CIBA-GEIGY AG (CH) 1980-11-26 — — EP disclosed
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