Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 14/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PDE2A | O00408 | 1/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.53 |
| ▸ | PDE6D | O43924 | 1/20 | 0.53 |
| ▸ | PDE8A | O60658 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141542 | 0.92 | SLC29A1 (0.61) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL4077877 | 0.91 | SLC29A1 (0.47) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL15065644 | 0.86 | SLC29A1 (0.55) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL7446848 | 0.85 | SLC29A1 (0.53) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL4417277 | 0.84 | SLC29A1 (0.47) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL7947717 | 0.79 | SLC29A1 (0.86) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL11045336 | 0.78 | SLC29A1 (0.47) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL2458642 | 0.78 | SLC29A1 (0.46) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL7953158 | 0.75 | SLC29A1 (0.74) | SLC29A1MAPTLMNAKDM4ETSHR | |
| SCHEMBL9565592 | 0.74 | SLC29A1 (0.49) | SLC29A1MAPTLMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031712-A1 | Therapeutic Compositions Containing Dipyridamole and Treatment Packs Including Such Compositions and Methods for Producing Same | O.D. OCULAR DISCOVERY LTD. (IL) | 2015-01-29 | — | — | US | disclosed |
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | BIOMOL INTERNATIONAL L.P. (US) | 2012-07-05 | — | — | US | disclosed |
| EP-0543653-A1 | Dipyridamole for the treatment of proliferative diseases | ELI LILLY AND COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| US-4292319-A | MIXTURE WITH AN ANTIULCER AGENT | BOEHRINGER INGELHEIM GMBH (DE) | 1981-09-29 | — | — | US | disclosed |
| US-4186136-A | COAGULANTS, ANTISPASMODIC AGENTS, ANALGESICS, ANTIINGLAMMATORY AGENTS, VASODILATION | INNOTHERA (FR) | 1980-01-29 | — | — | US | disclosed |
| US-4154833-A | INDOMETHACIN (1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETIC ACID) WITH PIRENZEPINE (5,11-DIHYDRO-11-((4-METHYL-1-PIPERAZINYL)-ACETYL)-6H-PYRIDO(2,3 -B)(1,4)BENZODIAZEPIN-6-ONE) | BOEHRINGER INGELHEIM GMBH (DE) | 1979-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172340-A1 | Compositions and Methods for Selectively Activating Human Sirtuins | SIRT1, SIRT7, SIRT5 | SLC29A1 4449/4885MAPT 3039/4885LMNA 1010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.