SCHEMBL7446848

SCHEMBL7446848

OCCON(OCCO)c1nc(N2CCCCC2)c2nc(Cl)nc(N3CCCCC3)c2n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 15/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ PDE4A P27815 2/20 0.53
▸ PDE4B Q07343 2/20 0.53
▸ PDE4C Q08493 2/20 0.53
▸ PDE4D Q08499 2/20 0.53
▸ ADORA3 P0DMS8 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ MEN1 O00255 1/20 0.53
▸ PDE2A O00408 1/20 0.53
▸ RGS12 O14924 1/20 0.53
▸ SLC22A2 O15244 1/20 0.53
▸ SLC22A1 O15245 1/20 0.53
▸ ABCC4 O15439 1/20 0.53
▸ ABCC5 O15440 1/20 0.53
▸ PDE6D O43924 1/20 0.53
▸ PDE8A O60658 1/20 0.53
▸ GMNN O75496 1/20 0.53
▸ USP2 O75604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141542 0.92 SLC29A1 (0.61) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL15065644 0.86 SLC29A1 (0.55) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL9565600 0.85 SLC29A1 (0.53) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL29973070 0.80 SLC29A1 (0.83) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL5055250 0.80 SLC29A1 (0.83) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL4077877 0.79 SLC29A1 (0.47) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL4417277 0.79 SLC29A1 (0.47) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL2458642 0.78 SLC29A1 (0.46) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL5315250 0.75 ALDH1A1 (0.46) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B
SCHEMBL10038311 0.73 SLC29A1 (0.75) SLC29A1ALDH1A1SMN1; SMN2PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8946414-B2 Processes for the preparation of dipyridamole GENERICS [UK] LIMITED (GB) 2015-02-03 — — US claimed
US-20130172369-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE GENERICS (UK) LIMITED (GB) 2013-07-04 — — US claimed
US-9381197-B2 Processes for the preparation of dipyridamole GENERICS [UK] LIMITED (GB) 2016-07-05 — — US disclosed
US-20150094320-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE GENERICS [UK] LIMITED (GB) 2015-04-02 — — US disclosed
US-8946414-B2 Processes for the preparation of dipyridamole GENERICS [UK] LIMITED (GB) 2015-02-03 — — US disclosed
US-20130172369-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE GENERICS (UK) LIMITED (GB) 2013-07-04 — — US disclosed
EP-2576562-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE Generics [UK] Limited (GB) 2013-04-10 — — EP disclosed
WO-2011151640-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE GENERICS [UK] LIMITED (GB) 2011-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150094320-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE QDPR, PEPD, DPP7 SLC29A1 904/4885ALDH1A1 1026/4885SMN1; SMN2 4824/4885
US-20130172369-A1 PROCESSES FOR THE PREPARATION OF DIPYRIDAMOLE QDPR, PEPD, DPP7 SLC29A1 904/4885ALDH1A1 1026/4885SMN1; SMN2 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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