SCHEMBL4078481

SCHEMBL4078481

Cc1cc(F)c(Br)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.31
KDM1B Q8NB78 2/20 0.31
ACHE P22303 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491276 0.79 RAPGEF4 (0.34) KDM1AKDM1BACHERAPGEF4
SCHEMBL28341279 0.79 RAPGEF4 (0.34) KDM1AKDM1BACHERAPGEF4
SCHEMBL31433854 0.78 ALDH1A1 (0.39) KDM1AKDM1B
SCHEMBL22063008 0.78 ALDH1A1 (0.39) KDM1AKDM1B
Hydrochloric Acid SCHEMBL34461204 0.77 ALDH1A1 (0.37) KDM1AKDM1B
SCHEMBL30567470 0.75 RAPGEF4 (0.38) ACHERAPGEF4
SCHEMBL2933659 0.75 CA1 (0.35) KDM1AKDM1B
SCHEMBL31258564 0.75 CA1 (0.35) KDM1AKDM1B
SCHEMBL823681 0.75 RAPGEF4 (0.38) ACHERAPGEF4
SCHEMBL1491275 0.74 HDAC1 (0.35) KDM1AKDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466770-A Preparation method of 2-nitro-4- (trifluoromethyl) benzonitrile 北京颖泰嘉和生物科技股份有限公司 2024-01-30 CN claimed
CN-116813475-A Halogenated synthesis method of aromatic ring compound 北京大学 2023-09-29 CN claimed
CN-114957312-A Aryl silicon compound of conjugated olefin and preparation method and application thereof 南京工业大学 2022-08-30 CN claimed
CN-113831275-A Indole-substituted 6-phenylindenoindole derivative and preparation method and application thereof 上海兆维科技发展有限公司 2021-12-24 CN claimed
CN-111439737-B Vanadium-based sodium oxyfluorophosphate type sodium battery positive electrode material and preparation method thereof 西安交通大学 2021-11-30 CN claimed
CN-113578395-A Pd/Fe-MOFs promote photocatalytic C-N and C-C bonding 重庆工商大学 2021-11-02 CN claimed
CN-110590767-B Method for synthesizing AMG837 南方科技大学 2021-10-08 CN claimed
CN-113437291-A Lithium vanadium fluorophosphosilicate cathode material and preparation method thereof 西安交通大学 2021-09-24 CN claimed
CN-113321935-A High-corrosion-resistance silicone rubber material and preparation method thereof 深圳市泰科科技有限公司 2021-08-31 CN claimed
CN-111446449-B Multi-electron-transmission vanadium-based oxygen sodium fluophosphate battery material and preparation method thereof 西安交通大学 2021-07-09 CN claimed
CN-112354551-A Novel monoatomic metal photocatalyst, preparation method thereof and application thereof in carbon-oxygen cross-coupling reaction 中国科学院化学研究所 2021-02-12 CN claimed
CN-111446449-A Multi-electron-transmission vanadium-based oxygen sodium fluophosphate battery material and preparation method thereof 西安交通大学 2020-07-24 CN claimed
CN-111439737-A Vanadium-based sodium oxyfluorophosphate type sodium battery positive electrode material and modified preparation method thereof 西安交通大学 2020-07-24 CN claimed
CN-110590767-A Method for synthesizing AMG837 南方科技大学 2019-12-20 CN claimed
US-7524992-B2 Carbon-carbon bond creation method comprising the coupling of a transferable group and an acceptor group RHODIA CHIMIE (FR) 2009-04-28 US claimed
US-20250215019-A1 ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-07-03 US disclosed
CN-120157620-A High-steric-hindrance dinaphthyl compound and application thereof in preparation of organic electroluminescent device 烟台显华科技集团股份有限公司 2025-06-17 CN disclosed
US-4871469-A TRIFLUOROTOLUENE DERIVATIVES BESCRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
EP-0002156-B1 7-AMINO-5H-BENZOCYCLOHEPTENE DERIVATIVES AND THEIR SALTS, A PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1981-05-13 EP disclosed
EP-0002156-A1 7-Amino-5H-benzocycloheptene derivatives and their salts, a process for their preparation, their use as medicines and pharmaceutical compositions containing them ROUSSEL-UCLAF (FR) 1979-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215019-A1 ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS BMP2, BMP4, DCX KDM1A 2623/4885KDM1B 2101/4885ACHE 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.