Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8602910 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL5369683 | 0.80 | GABRA1 (0.32) | GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL9421533 | 0.76 | GABRA1 (0.34) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Hydrochloric Acid SCHEMBL5583459 | 0.76 | GABRA1 (0.34) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Hydrochloric Acid SCHEMBL27463390 | 0.76 | GABRA1 (0.34) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Hydrochloric Acid SCHEMBL29612295 | 0.75 | GABRA1 (0.33) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Hydrochloric Acid SCHEMBL1685534 | 0.75 | GABRA1 (0.33) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Hydrochloric Acid SCHEMBL27478549 | 0.75 | FABP4 (0.33) | GABRA1GABRB2FABP3FABP4FABP5 | |
| Hydrochloric Acid SCHEMBL8604522 | 0.75 | GABRA1 (0.31) | GABRA1GABRB2FABP3FABP4 | |
| Hydrochloric Acid SCHEMBL385357 | 0.75 | GABRA1 (0.31) | GABRA1GABRB2FABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044155-B2 | Coordination polymerization catalyst containing magnesium compound, titanium compound and organoaluminum compound | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2011-10-25 | — | — | US | disclosed |
| EP-1716185-B1 | Titanocene-based catalyst system | STICHTING DUTCH POLYMER INST (NL) | 2009-10-21 | — | — | EP | disclosed |
| US-20080234452-A1 | TITANOCENE-BASED CATALYST SYSTEM | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2008-09-25 | — | — | US | disclosed |
| US-20070179049-A1 | Titanocenen-based catalyst system | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2007-08-02 | — | — | US | disclosed |
| EP-1564226-A1 | Titanocene-based catalyst system | Stichting Dutch Polymer Institute (NL) | 2005-08-17 | — | — | EP | disclosed |