Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 7/20 | 0.59 |
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | DRD2 | P14416 | 6/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079207 | 0.90 | DRD2 (0.64) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4081131 | 0.81 | DRD2 (0.59) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4081134 | 0.81 | DRD2 (0.59) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4078880 | 0.81 | CRHBP (0.59) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4079602 | 0.81 | HTR7 (0.55) | HTR7HTR2ADRD3DRD2THRB | |
| SCHEMBL4075434 | 0.80 | DRD2 (0.56) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4088191 | 0.79 | DRD2 (0.57) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4075285 | 0.77 | DRD3 (0.57) | HTR7HTR2ADRD3DRD2HTR1A | |
| SCHEMBL4485092 | 0.75 | DRD3 (0.70) | HTR2ADRD3DRD2HTR1AHTR2C | |
| SCHEMBL13629885 | 0.75 | DRD3 (0.70) | HTR2ADRD3DRD2HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |