SCHEMBL4079383

SCHEMBL4079383

Cc1cc(N(c2ccccc2)c2cccc3c2oc2ccccc23)c2ccc3c(C)cc(N(c4ccccc4)c4cccc5c4oc4ccccc45)c4ccc1c2c34

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.35
ALOX5 P09917 3/20 0.34
TTR P02766 1/20 0.34
PGR P06401 1/20 0.33
CYP1A2 P05177 1/20 0.33
HPGD P15428 3/20 0.32
KDM4E B2RXH2 2/20 0.32
GAA P10253 2/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 1/20 0.32
AHR P35869 2/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TOP2A P11388 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP2C19 P33261 1/20 0.31
CYP3A4 P08684 1/20 0.31
ALPI P09923 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18101682 0.97 MAOA (0.35) MAOAALOX5TTRPGRCYP1A2
SCHEMBL12206540 0.93 HPGD (0.38) MAOAALOX5TTRPGRHPGD
SCHEMBL4088972 0.93 ALOX5 (0.36) MAOAALOX5TTRPGRCYP1A2
SCHEMBL21163906 0.92 ALOX5 (0.33) MAOAALOX5TTRPGRCYP1A2
SCHEMBL17342373 0.92 MAOA (0.32) MAOAALOX5TTRPGRCYP1A2
SCHEMBL17342410 0.91 MAOA (0.34) MAOAALOX5TTRPGRCYP1A2
SCHEMBL17342444 0.91 ALOX5 (0.33) MAOAALOX5TTRPGRHPGD
SCHEMBL26246513 0.91 CNR2 (0.30) MAOA
SCHEMBL4079386 0.90 ALOX5 (0.36) MAOAALOX5TTRPGRHPGD
SCHEMBL16216472 0.89 MCL1 (0.34) MAOAKMT2AMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210288263-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-09-16 US disclosed
US-10570113-B2 Aromatic amine derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-25 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-8431250-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2013-04-30 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-05-10 US disclosed
US-20110248246-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-10-13 US disclosed
US-20110248246-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120112169-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AR, H1-4, AFF4 MAOA 144/4885ALOX5 3494/4885TTR 2454/4885
US-20110248246-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE AHR, ADRA1A, ADRA1D MAOA 260/4885ALOX5 2176/4885TTR 3977/4885
US-10570113-B2 Aromatic amine derivative, light-emitting element, light-emitting device, electronic device, and lighting device AHR, ADRA1A, ADRA1D MAOA 250/4885ALOX5 2107/4885TTR 3963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.