Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.54 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078880 | 0.90 | CRHBP (0.59) | HTR7LMNASMN1; SMN2DRD3DRD2 | |
| SCHEMBL4084678 | 0.86 | DRD2 (0.57) | HTR7LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL4079160 | 0.82 | DRD2 (0.60) | HTR7DRD3DRD2HTR2AHTR1A | |
| SCHEMBL4079163 | 0.82 | DRD2 (0.60) | HTR7DRD3DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL4079619 | 0.81 | DRD2 (0.59) | HTR7DRD3DRD2HTR2AHTR1A | |
| Hydrochloric Acid SCHEMBL4079616 | 0.81 | DRD2 (0.59) | HTR7DRD3DRD2HTR2AHTR1A | |
| SCHEMBL4083822 | 0.81 | HTR2A (0.61) | DRD3DRD2HTR2AHTR1A | |
| SCHEMBL4075504 | 0.81 | HTR7 (0.65) | HTR7MAPTTHRBDRD3DRD2 | |
| SCHEMBL4075532 | 0.79 | DRD2 (0.54) | HTR7DRD3DRD2HTR2AKCNH2 | |
| SCHEMBL4075285 | 0.78 | DRD3 (0.57) | HTR7DRD3DRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |