Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607070 | 0.97 | KDM4E (0.44) | KDM4ETP53BBOX1CTDSP1TSHR | |
| SCHEMBL2866854 | 0.97 | KDM4E (0.44) | KDM4ETP53BBOX1CTDSP1TSHR | |
| SCHEMBL372419 | 0.97 | — | — | |
| Iodide SCHEMBL2456403 | 0.94 | KDM4E (0.48) | KDM4ETP53BBOX1CTDSP1TSHR | |
| Fluoride Ion SCHEMBL30330915 | 0.94 | KDM4E (0.42) | KDM4ETP53BBOX1CTDSP1TSHR | |
| Bromide SCHEMBL9328011 | 0.94 | TP53 (0.46) | KDM4ETP53BBOX1CTDSP1TSHR | |
| SCHEMBL10851035 | 0.94 | KDM4E (0.42) | KDM4ETP53BBOX1CTDSP1TSHR | |
| Hydrochloric Acid SCHEMBL9198276 | 0.94 | KDM4E (0.42) | KDM4ETP53BBOX1CTDSP1TSHR | |
| SCHEMBL142703 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL556790 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709309-B | Process for producing fluorine-containing cyclopropanecarboxylic acid | 中央硝子株式会社 | 2020-10-09 | — | — | CN | disclosed |
| US-7504527-B2 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC (US) | 2009-03-17 | — | — | US | disclosed |
| US-7491837-B2 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING LLC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7145029-B2 | Low corrosive integrated process for preparing dialkyl carbonates | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-12-05 | — | — | US | disclosed |
| EP-1490323-A1 | A LOW CORROSIVE INTEGRATED PROCESS FOR PREPARING DIALKYL CARBONATES | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040236136-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2004-11-25 | — | — | US | disclosed |
| US-6774256-B2 | Low corrosive integrated process for preparing dialkyl carbonates | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-08-10 | — | — | US | disclosed |
| US-20040059083-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2004-03-25 | — | — | US | disclosed |
| US-20040054214-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2004-03-18 | — | — | US | disclosed |
| WO-2003082797-A1 | A LOW CORROSIVE INTEGRATED PROCESS FOR PREPARING DIALKYL CARBONATES | EXXONMOBIL CHEMICAL PATENTS INC. A CORPORATION OF THE STATE OF DELAWARE (US) | 2003-10-09 | — | — | WO | disclosed |
| US-20030023109-A1 | Low corrosive integrated process for preparing dialkyl carbonates | BADGER LICENSING, LLC | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236136-A1 | Low corrosive integrated process for preparing dialkyl carbonates | DCLK1, DGKI, GALK1 | KDM4E 1816/4885TP53 4697/4885BBOX1 3168/4885 |
| US-20040054214-A1 | Low corrosive integrated process for preparing dialkyl carbonates | DCLK1, DGKI, GALK1 | KDM4E 1816/4885TP53 4697/4885BBOX1 3168/4885 |
| US-20030023109-A1 | Low corrosive integrated process for preparing dialkyl carbonates | DCLK1, DGKI, GALK1 | KDM4E 1816/4885TP53 4697/4885BBOX1 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.