Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206648 | 0.89 | ALDH1A1 (0.42) | EPHX2THRBHPGDSIGMAR1ALDH1A1 | |
| SCHEMBL4079453 | 0.88 | LMNA (0.43) | HPGDSIGMAR1OPRM1OPRL1SSTR1 | |
| SCHEMBL205753 | 0.88 | SIGMAR1 (0.45) | EPHX2THRBHPGDSIGMAR1OPRM1 | |
| SCHEMBL206650 | 0.87 | KMT2A (0.44) | EPHX2THRBHPGDSIGMAR1ALDH1A1 | |
| SCHEMBL206966 | 0.86 | EPHX2 (0.62) | EPHX2THRBHPGDSIGMAR1GAA | |
| SCHEMBL206577 | 0.85 | SIGMAR1 (0.43) | EPHX2THRBHPGDSIGMAR1OPRM1 | |
| SCHEMBL206443 | 0.85 | EPHX2 (0.42) | EPHX2THRBHPGDSIGMAR1ALDH1A1 | |
| SCHEMBL207872 | 0.85 | SIGMAR1 (0.46) | EPHX2THRBHPGDSIGMAR1OPRM1 | |
| SCHEMBL206084 | 0.83 | EPHX2 (0.47) | EPHX2THRBHPGDSIGMAR1OPRM1 | |
| SCHEMBL205975 | 0.83 | SIGMAR1 (0.41) | EPHX2THRBHPGDSIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |