Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL441034 | 0.99 | ALDH1A1 (0.60) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL12719906 | 0.85 | ALDH1A1 (0.62) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL21768192 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL463651 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL12297020 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL6983366 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL6983363 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL12284386 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL5605817 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TSHRNPC1RAB9AMAPT | |
| SCHEMBL10039631 | 0.78 | ALDH1A1 (0.66) | ALDH1A1TSHRNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | ALDH1A1 272/4885TSHR 2375/4885NPC1 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.