SCHEMBL5605817

SCHEMBL5605817

CCOC(=O)C1CCN(C(=O)CCCN2CCOCC2)CC1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.57
RAB9A P51151 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
TSHR P16473 3/20 0.55
NPC1 O15118 1/20 0.55
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
MAPT P10636 2/20 0.50
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPK10 P53779 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18039877 0.85 MAPT (0.54) ALDH1A1TSHRLMNAMAPTSMN1; SMN2
SCHEMBL18039931 0.84 ALDH1A1 (0.57) ALDH1A1TSHRLMNAPOLBMAPT
SCHEMBL5606028 0.81 KDM1A (0.48) ALDH1A1RAB9AL3MBTL1TSHRNPC1
SCHEMBL12719906 0.79 ALDH1A1 (0.62) ALDH1A1RAB9AL3MBTL1TSHRNPC1
SCHEMBL408106 0.79 ALDH1A1 (0.62) ALDH1A1RAB9ATSHRNPC1MAPT
SCHEMBL11454925 0.78 LMNA (0.54) ALDH1A1L3MBTL1LMNAMAPTHSD17B10
SCHEMBL1127670 0.78 L3MBTL1 (0.63) ALDH1A1RAB9AL3MBTL1TSHRLMNA
SCHEMBL15569388 0.78 MAPT (0.62) ALDH1A1LMNAMAPTSMN1; SMN2
Hydrochloric Acid SCHEMBL441034 0.78 ALDH1A1 (0.60) ALDH1A1RAB9ATSHRNPC1MAPT
SCHEMBL3959932 0.77 GNAI3 (0.54) ALDH1A1RAB9AL3MBTL1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166594-B2 Antibacterial activity AVENTIS PHARMA S.A. (FR) 2007-01-23 US disclosed
US-20030149004-A1 Streptogramin derivatives, their preparation and compositions containing them AVENTIS PHARMA S.A. 2003-08-07 US disclosed
US-6569854-B1 Virginamycins AVENTIS PHARMA S.A. (FR) 2003-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149004-A1 Streptogramin derivatives, their preparation and compositions containing them MRPL21, ABHD5, APEH ALDH1A1 4296/4885RAB9A 2288/4885L3MBTL1 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.