Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207763 | 0.88 | CYP2D6 (0.38) | SSTR4SSTR1MEN1KMT2AOPRM1 | |
| SCHEMBL4079658 | 0.86 | SSTR4 (0.43) | SSTR4SSTR1MEN1KMT2AOPRM1 | |
| SCHEMBL206824 | 0.84 | L3MBTL1 (0.47) | L3MBTL1SSTR4SSTR1MEN1KMT2A | |
| SCHEMBL207190 | 0.81 | ALDH1A1 (0.43) | SSTR4SSTR1MEN1KMT2ACYP2D6 | |
| SCHEMBL4052851 | 0.81 | KMT2A (0.48) | SSTR4SSTR1MEN1KMT2AOPRM1 | |
| SCHEMBL5157976 | 0.80 | SSTR4 (0.45) | SSTR4SSTR1MEN1KMT2AOPRM1 | |
| SCHEMBL206665 | 0.80 | SSTR4 (0.45) | SSTR4SSTR1MEN1KMT2AOPRM1 | |
| SCHEMBL206981 | 0.80 | DRD4 (0.41) | SSTR4SSTR1MEN1KMT2A | |
| SCHEMBL205964 | 0.80 | METAP2 (0.43) | SSTR4SSTR1 | |
| SCHEMBL206157 | 0.80 | NPC1 (0.46) | SSTR4SSTR1MEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |