Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206439 | 0.90 | HDAC1 (0.42) | AVPR1AOXTROPRM1OPRL1HDAC1 | |
| SCHEMBL4073137 | 0.85 | OPRM1 (0.43) | EPHX2OPRM1OPRL1 | |
| SCHEMBL4074077 | 0.82 | OPRM1 (0.51) | EPHX2OPRM1OPRL1 | |
| SCHEMBL4074080 | 0.81 | OPRM1 (0.51) | EPHX2OPRM1OPRL1 | |
| SCHEMBL4083177 | 0.79 | OPRM1 (0.47) | OPRM1OPRL1KMT2A | |
| SCHEMBL4079677 | 0.79 | OPRM1 (0.47) | EPHX2OPRM1OPRL1 | |
| SCHEMBL206923 | 0.78 | OPRM1 (0.43) | OPRM1OPRL1KMT2A | |
| SCHEMBL4079674 | 0.76 | OPRM1 (0.45) | EPHX2OPRM1OPRL1 | |
| SCHEMBL4079669 | 0.76 | OPRM1 (0.45) | EPHX2OPRM1OPRL1 | |
| SCHEMBL4085419 | 0.76 | OPRM1 (0.45) | EPHX2OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |