Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GRK2 | P25098 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569037 | 1.00 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13568880 | 0.90 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL4074184 | 0.90 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL4075143 | 0.88 | GRK2 (0.62) | SMN1; SMN2MEN1KMT2APOLBTDP1 | |
| SCHEMBL13569028 | 0.88 | GRK2 (0.62) | SMN1; SMN2MEN1KMT2APOLBTDP1 | |
| SCHEMBL13568966 | 0.85 | POLB (0.50) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13569005 | 0.85 | CA2 (0.59) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13568977 | 0.85 | MEN1 (0.48) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL4073741 | 0.85 | MEN1 (0.48) | RAB9ASMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL13568962 | 0.84 | ESR1 (0.63) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |