Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.59 |
| ▸ | CA9 | Q16790 | 9/20 | 0.59 |
| ▸ | CA1 | P00915 | 8/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082049 | 0.85 | RAB9A (0.66) | CA2CA9CA1MAPTMEN1 | |
| SCHEMBL13569037 | 0.85 | RAB9A (0.66) | CA2CA9CA1MAPTMEN1 | |
| SCHEMBL4074184 | 0.82 | RAB9A (0.60) | CA2CA9CA1MAPTMEN1 | |
| SCHEMBL13568880 | 0.82 | RAB9A (0.60) | CA2CA9CA1MAPTMEN1 | |
| SCHEMBL13569028 | 0.81 | GRK2 (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4075143 | 0.81 | GRK2 (0.62) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10061533 | 0.79 | CA2 (0.72) | CA2CA9CA1CA12ALDH1A1 | |
| SCHEMBL13568966 | 0.78 | POLB (0.50) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL4073741 | 0.78 | MEN1 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13568977 | 0.78 | MEN1 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |