Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL665105

Brc1ccc2c(c1)Cc1ccccc1-2.N

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
KDM4E B2RXH2 1/20 0.57
NPC1 O15118 1/20 0.57
LMNA P02545 1/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
SRD5A2 P31213 1/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CYP1A2 P05177 3/20 0.47
CYP3A4 P08684 2/20 0.47
METAP1 P53582 1/20 0.47
TRPA1 O75762 1/20 0.46
TDP2 O95551 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL15453329 0.98 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL415882 0.98 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL29780658 0.98 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL29466104 0.98 ALDH1A1 (0.59) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL17313627 0.92 SMN1; SMN2 (0.53) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL23542831 0.89 L3MBTL1 (0.56) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL19237245 0.89 L3MBTL1 (0.56) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL1806266 0.89 L3MBTL1 (0.56) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
Ammonia Solution, Strong SCHEMBL28144371 0.89 METAP1 (0.55) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1
SCHEMBL29376113 0.87 METAP1 (0.57) ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8419808-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2013-04-16 US disclosed
US-8203068-B2 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2012-06-19 US disclosed
US-20120042457-A1 DYE COMPOUND AND PHOTOELECTRIC COMPONENT USING THE SAME EVERLIGHT USA, INC. (US) 2012-02-23 US disclosed
US-20110100462-A1 Dye-sensitized solar cell and photoanode thereof EVERLIGHT USA, INC. (US) 2011-05-05 US disclosed
US-20100122729-A1 Dye compound and photoelectric component using the same EVERLIGHT USA, INC. (US) 2010-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120042457-A1 DYE COMPOUND AND PHOTOELECTRIC COMPONENT USING THE SAME CRY1, SCNN1B, SMARCC2 ALDH1A1 491/4885RAB9A 1440/4885SMN1; SMN2 3352/4885
US-20100122729-A1 Dye compound and photoelectric component using the same CRY1, SCNN1B, SMARCC2 ALDH1A1 491/4885RAB9A 1440/4885SMN1; SMN2 3352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.