Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416467 | 0.83 | TGFBR1 (0.46) | TGFBR1NOD1OPRM1OPRD1OPRK1 | |
| SCHEMBL29630639 | 0.82 | TGFBR1 (0.42) | TGFBR1OPRM1OPRD1OPRK1MME | |
| SCHEMBL4097970 | 0.81 | TGFBR1 (0.45) | TGFBR1NOD1MME | |
| SCHEMBL29590315 | 0.81 | PTGS1 (0.42) | TGFBR1OPRM1OPRD1OPRK1MME | |
| SCHEMBL29867949 | 0.81 | PTGS1 (0.42) | TGFBR1OPRM1OPRD1OPRK1MME | |
| SCHEMBL29528046 | 0.81 | TGFBR1 (0.43) | TGFBR1NOD1OPRM1OPRD1OPRK1 | |
| SCHEMBL29527284 | 0.81 | TGFBR1 (0.43) | TGFBR1NOD1OPRM1OPRD1OPRK1 | |
| SCHEMBL29540545 | 0.81 | PTGS1 (0.43) | TGFBR1NOD1OPRM1OPRD1OPRK1 | |
| SCHEMBL29528171 | 0.81 | TGFBR1 (0.43) | TGFBR1NOD1OPRM1OPRD1OPRK1 | |
| SCHEMBL29382390 | 0.81 | TGFBR1 (0.43) | TGFBR1NOD1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | TGFBR1 2913/4885PDCD1LG2 4789/4885CD274 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.